Cargando…

METHODS - A randomised controlled trial of METhotrexate to treat Hand Osteoarthritis with Synovitis: study protocol for a randomised controlled trial

BACKGROUND: Hand osteoarthritis is a common and disabling problem without effective therapies. Accumulating evidence suggests the role of local inflammation in causing pain and structural progression in hand osteoarthritis, and hand osteoarthritis with synovitis is a commonly encountered clinical ph...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Yuanyuan, Teichtahl, Andrew J., Jones, Graeme, Keen, Helen I., Hill, Catherine L., Wluka, Anita E., Kasza, Jessica, Cicuttini, Flavia M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Study Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591971/ https://www.ncbi.nlm.nih.gov/pubmed/34781952 http://dx.doi.org/10.1186/s12891-021-04842-0

Ejemplares similares

Study protocol for a randomised controlled trial of diacerein versus placebo to treat knee osteoarthritis with effusion-synovitis (DICKENS)
por: Cai, Guoqi, et al.
Publicado: (2022)

Topical corticosteroid for treatment of hand osteoarthritis: study protocol for a randomised controlled trial
por: Wang, Yuanyuan, et al.
Publicado: (2021)

Patterns and natural history of hand pain in individuals with symptomatic hand osteoarthritis in a prospective cohort study: A post-hoc analysis of a randomised controlled trial
por: Estee, Mahnuma Mahfuz, et al.
Publicado: (2023)

Does statin use have a disease modifying effect in symptomatic knee osteoarthritis? Study protocol for a randomised controlled trial
por: Wang, Yuanyuan, et al.
Publicado: (2015)

Effect of low-dose amitriptyline on reducing pain in clinical knee osteoarthritis compared to benztropine: study protocol of a randomised, double blind, placebo-controlled trial
por: Wluka, Anita E., et al.
Publicado: (2021)

Effect of atorvastatin on skeletal muscles of patients with knee osteoarthritis: Post-hoc analysis of a randomised controlled trial
por: Lim, Yuan Z., et al.
Publicado: (2022)

KARAOKE: Krill oil versus placebo in the treatment of knee osteoarthritis: protocol for a randomised controlled trial
por: Laslett, L. L., et al.
Publicado: (2020)

Efficacy of tumor necrosis factor inhibitors in hand osteoarthritis: A systematic review and meta-analysis of randomized controlled trials
por: Estee, Mahnuma Mahfuz, et al.
Publicado: (2023)

Efficacy of corticosteroids for hand osteoarthritis - a systematic review and meta-analysis of randomized controlled trials
por: Estee, Mahnuma Mahfuz, et al.
Publicado: (2022)

A protocol for a multicentre, randomised, double-blind, placebo-controlled trial to compare the effect of annual infusions of zoledronic acid to placebo on knee structural change and knee pain over 24 months in knee osteoarthritis patients – ZAP2
por: Aitken, Dawn, et al.
Publicado: (2018)

Can low-dose methotrexate reduce effusion-synovitis and symptoms in patients with mid- to late-stage knee osteoarthritis? Study protocol for a randomised, double-blind, and placebo-controlled trial
por: Zhu, Zhaohua, et al.
Publicado: (2020)

Wolff’s law in action: a mechanism for early knee osteoarthritis
por: Teichtahl, Andrew J., et al.
Publicado: (2015)

Vitamin D supplementation in the management of knee osteoarthritis: study protocol for a randomized controlled trial
por: Cao, Yuelong, et al.
Publicado: (2012)

Effect of 6-week treatment with topical betamethasone dipropionate in patients with symptomatic hand osteoarthritis: A randomized double-blind, placebo-controlled trial
por: Wang, Yuanyuan, et al.
Publicado: (2023)

Factors that may mediate the relationship between physical activity and the risk for developing knee osteoarthritis
por: Urquhart, Donna M, et al.
Publicado: (2008)

Footwear for osteoarthritis of the lateral knee: protocol for the FOLK randomised controlled trial
por: Paterson, Kade L., et al.
Publicado: (2020)

Structural changes of hip osteoarthritis using magnetic resonance imaging
por: Teichtahl, Andrew J, et al.
Publicado: (2014)

Occupational risk factors for hip osteoarthritis are associated with early hip structural abnormalities: a 3.0 T magnetic resonance imaging study of community-based adults
por: Teichtahl, Andrew J, et al.
Publicado: (2015)

Lateral wedge insoles for medial knee osteoarthritis: 12 month randomised controlled trial
por: Bennell, Kim L, et al.
Publicado: (2011)

Impact of intravenous abatacept on synovitis, osteitis and structural damage in patients with rheumatoid arthritis and an inadequate response to methotrexate: the ASSET randomised controlled trial
por: Conaghan, Philip G, et al.
Publicado: (2013)

Knee cartilage loss in symptomatic knee osteoarthritis over 4.5 years
por: Wluka, Anita E, et al.
Publicado: (2006)

Relationship between body adiposity measures and risk of primary knee and hip replacement for osteoarthritis: a prospective cohort study
por: Wang, Yuanyuan, et al.
Publicado: (2009)

Is low-dose amitriptyline effective in the management of chronic low back pain? Study protocol for a randomised controlled trial
por: Urquhart, Donna M., et al.
Publicado: (2016)

Lateral wedge shoe insoles for medial knee osteoarthritis: a 12-month randomised controlled trial
por: Bennell, Kim L, et al.
Publicado: (2011)

Modic changes in the lumbar spine and their association with body composition, fat distribution and intervertebral disc height – a 3.0 T-MRI study
por: Teichtahl, Andrew J., et al.
Publicado: (2016)

Physical inactivity is associated with narrower lumbar intervertebral discs, high fat content of paraspinal muscles and low back pain and disability
por: Teichtahl, Andrew J, et al.
Publicado: (2015)

Lumbar disc degeneration is associated with modic change and high paraspinal fat content – a 3.0T magnetic resonance imaging study
por: Teichtahl, Andrew J., et al.
Publicado: (2016)

Shoe-stiffening inserts for first metatarsophalangeal joint osteoarthritis (the SIMPLE trial): study protocol for a randomised controlled trial
por: Munteanu, Shannon E., et al.
Publicado: (2017)

Self management, joint protection and exercises in hand osteoarthritis: a randomised controlled trial with cost effectiveness analyses
por: Dziedzic, Krysia S, et al.
Publicado: (2011)

Response to: ‘A dose–response relationship between severity of disc degeneration and intervertebral disc height in the lumbosacral spine’—authors’ reply
por: Teichtahl, Andrew J., et al.
Publicado: (2016)

A Dose–response relationship between severity of disc degeneration and intervertebral disc height in the lumbosacral spine
por: Teichtahl, Andrew J., et al.
Publicado: (2015)

Is antibiotic treatment effective in the management of chronic low back pain with disc herniation? Study protocol for a randomised controlled trial
por: Urquhart, Donna M., et al.
Publicado: (2021)

Patients’ perceived needs of osteoarthritis health information: A systematic scoping review
por: Chou, Louisa, et al.
Publicado: (2018)

Meniscal pathology - the evidence for treatment
por: Mezhov, Veronica, et al.
Publicado: (2014)

Associations between systemic bone mineral density and early knee cartilage changes in middle-aged adults without clinical knee disease: a prospective cohort study
por: Teichtahl, Andrew J., et al.
Publicado: (2017)

Foot orthoses for first metatarsophalangeal joint osteoarthritis: study protocol for the FORT randomised controlled trial
por: Paterson, Kade L., et al.
Publicado: (2020)

Effect of breakfast on weight and energy intake: systematic review and meta-analysis of randomised controlled trials
por: Sievert, Katherine, et al.
Publicado: (2019)

Functional consultation and exercises improve grip strength in osteoarthritis of the hand – a randomised controlled trial
por: Stoffer-Marx, Michaela A., et al.
Publicado: (2018)

The associations between indices of patellofemoral geometry and knee pain and patella cartilage volume: a cross-sectional study
por: Tanamas, Stephanie K, et al.
Publicado: (2010)

Weight change following knee and hip joint arthroplasty–a six-month prospective study of adults with osteoarthritis
por: Teichtahl, Andrew J, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_hilp4b38dbhbf718qnjb5il6kq