Suppressing STAT3 activity protects the endothelial barrier from VEGF-mediated vascular permeability

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Vascular permeability triggered by inflammation or ischemia promotes edema, exacerbates disease progression and impairs tissue recovery. Vascular endothelial growth factor (VEGF) is a potent inducer of vascular permeability. VEGF plays an integral role in regulating vascular barrier function physiol...

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Detalles Bibliográficos
Autores principales: Wang, Li, Astone, Matteo, Alam, Sk. Kayum, Zhu, Zhu, Pei, Wuhong, Frank, David A., Burgess, Shawn M., Hoeppner, Luke H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592016/
https://www.ncbi.nlm.nih.gov/pubmed/34542605
http://dx.doi.org/10.1242/dmm.049029
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