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Growth-dependent signals drive an increase in early G1 cyclin concentration to link cell cycle entry with cell growth

Entry into the cell cycle occurs only when sufficient growth has occurred. In budding yeast, the cyclin Cln3 is thought to initiate cell cycle entry by inactivating a transcriptional repressor called Whi5. Growth-dependent changes in the concentrations of Cln3 or Whi5 have been proposed to link cell...

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Detalles Bibliográficos
Autores principales: Sommer, Robert A, DeWitt, Jerry T, Tan, Raymond, Kellogg, Douglas R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592568/
https://www.ncbi.nlm.nih.gov/pubmed/34713806
http://dx.doi.org/10.7554/eLife.64364