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Gambogic amide inhibits angiogenesis by suppressing VEGF/VEGFR2 in endothelial cells in a TrkA-independent manner

CONTEXT: Gambogic amide (GA-amide) is a non-peptide molecule that has high affinity for tropomyosin receptor kinase A (TrkA) and possesses robust neurotrophic activity, but its effect on angiogenesis is unclear. OBJECTIVE: The study investigates the antiangiogenic effect of GA-amide on endothelial c...

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Detalles Bibliográficos
Autores principales:	Sui, Tongtong, Qiu, Bojun, Qu, Jiaorong, Wang, Yuxin, Ran, Kunnian, Han, Wei, Peng, Xiaozhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592593/ https://www.ncbi.nlm.nih.gov/pubmed/34767490 http://dx.doi.org/10.1080/13880209.2021.1998140

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