Rapid and improved oral absorption of N-butylphthalide by sodium cholate-appended liposomes for efficient ischemic stroke therapy

As a multi-target drug to treat ischemic stroke, N-butylphthalide (NBP) is extremely water-insoluble and exhibits limited oral bioavailability, impeding its wide oral application. Effective treatment of ischemic stroke by NBP requires timely and efficient drug exposure, necessitating the development...

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Detalles Bibliográficos
Autores principales: Zhang, Ailing, Li, Jianbo, Wang, Shuaishuai, Xu, Yaru, Li, Qinglian, Wu, Zhe, Wang, Chenxu, Meng, Haiyang, Zhang, Jinjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592624/
https://www.ncbi.nlm.nih.gov/pubmed/34766542
http://dx.doi.org/10.1080/10717544.2021.2000678

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