PEI-PEG-Coated Mesoporous Silica Nanoparticles Enhance the Antitumor Activity of Tanshinone IIA and Serve as a Gene Transfer Vector

Tanshinone IIA (TanIIA) and gene therapy both hold promising potentials in hepatocellular carcinoma (HCC) treatment. However, low solubility and poor bioavailability of TanIIA limit its clinical application. Similarly, gene therapy with GPC3-shRNA, a type of short hairpin RNAs (shRNAs) capable of si...

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Detalles Bibliográficos
Autores principales: Zhu, Yinxing, Yue, Miao, Guo, Ting, Li, Fang, Li, Zhifeng, Yang, Dazhuang, Lin, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592735/
https://www.ncbi.nlm.nih.gov/pubmed/34790248
http://dx.doi.org/10.1155/2021/6756763

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