Inhibition of the PERK/TXNIP/NLRP3 Axis by Baicalin Reduces NLRP3 Inflammasome-Mediated Pyroptosis in Macrophages Infected with Mycobacterium tuberculosis

Mycobacterium tuberculosis (Mtb) remains a significant threat to global health as it induces granuloma and systemic inflammatory responses during active tuberculosis. Mtb can induce macrophage pyroptosis, leading to the release of IL-1β and tissue damage, promoting its spread. Here, we established a...

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Detalles Bibliográficos
Autores principales: Fu, Yan, Shen, Jingjing, Li, Yinhong, Liu, Fanglin, Ning, Bangzuo, Zheng, Yuejuan, Jiang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592748/
https://www.ncbi.nlm.nih.gov/pubmed/34790063
http://dx.doi.org/10.1155/2021/1805147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592748/
https://www.ncbi.nlm.nih.gov/pubmed/34790063
http://dx.doi.org/10.1155/2021/1805147

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