Cargando…

Inhibition of the PERK/TXNIP/NLRP3 Axis by Baicalin Reduces NLRP3 Inflammasome-Mediated Pyroptosis in Macrophages Infected with Mycobacterium tuberculosis

Mycobacterium tuberculosis (Mtb) remains a significant threat to global health as it induces granuloma and systemic inflammatory responses during active tuberculosis. Mtb can induce macrophage pyroptosis, leading to the release of IL-1β and tissue damage, promoting its spread. Here, we established a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fu, Yan, Shen, Jingjing, Li, Yinhong, Liu, Fanglin, Ning, Bangzuo, Zheng, Yuejuan, Jiang, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592748/ https://www.ncbi.nlm.nih.gov/pubmed/34790063 http://dx.doi.org/10.1155/2021/1805147

Ejemplares similares

Baicalein Suppresses NLRP3 and AIM2 Inflammasome-Mediated Pyroptosis in Macrophages Infected by Mycobacterium tuberculosis via Induced Autophagy
por: Ning, Bangzuo, et al.
Publicado: (2023)

Corilagin Restrains NLRP3 Inflammasome Activation and Pyroptosis through the ROS/TXNIP/NLRP3 Pathway to Prevent Inflammation
por: Luo, Tianyu, et al.
Publicado: (2022)

Pyroptosis in NLRP3 inflammasome-related atherosclerosis
por: Zeng, Xiang, et al.
Publicado: (2022)

Viral Glycoproteins Induce NLRP3 Inflammasome Activation and Pyroptosis in Macrophages
por: Eisfeld, Hannah S., et al.
Publicado: (2021)

Ceramide induces pyroptosis through TXNIP/NLRP3/GSDMD pathway in HUVECs
por: Liu, Fangfang, et al.
Publicado: (2022)

Role of ASM/Cer/TXNIP signaling module in the NLRP3 inflammasome activation
por: Jiang, Jianjun, et al.
Publicado: (2021)

Punicalagin Protects Diabetic Nephropathy by Inhibiting Pyroptosis Based on TXNIP/NLRP3 Pathway
por: An, Xin, et al.
Publicado: (2020)

PARP-1 regulates inflammasome activity by poly-ADP-ribosylation of NLRP3 and interaction with TXNIP in primary macrophages
por: Chiu, Ling-Ya, et al.
Publicado: (2022)

Emerging Role of NLRP3 Inflammasome/Pyroptosis in Huntington’s Disease
por: Paldino, Emanuela, et al.
Publicado: (2022)

Emerging Role of NLRP3 Inflammasome and Pyroptosis in Liver Transplantation
por: Lucas-Ruiz, Fernando, et al.
Publicado: (2022)

NLRP3 inflammasome-induced pyroptosis in digestive system tumors
por: Wen, Jiexia, et al.
Publicado: (2023)

Receptor for Advanced Glycation End-Products Promotes Activation of Alveolar Macrophages through the NLRP3 Inflammasome/TXNIP Axis in Acute Lung Injury
por: Lenga Ma Bonda, Woodys, et al.
Publicado: (2022)

NLRP3 licenses NLRP11 for inflammasome activation in human macrophages
por: Gangopadhyay, Anu, et al.
Publicado: (2022)

Andrographolide Suppresses Pyroptosis in Mycobacterium tuberculosis-Infected Macrophages via the microRNA-155/Nrf2 Axis
por: Fu, Yan, et al.
Publicado: (2022)

MiR-17-5p Inhibits TXNIP/NLRP3 Inflammasome Pathway and Suppresses Pancreatic β-Cell Pyroptosis in Diabetic Mice
por: Liu, Sijun, et al.
Publicado: (2021)

Baicalin ameliorates atherosclerosis by inhibiting NLRP3 inflammasome in apolipoprotein E-deficient mice
por: Zhao, Jingfei, et al.
Publicado: (2020)

Chrysin ameliorates synovitis and fibrosis of osteoarthritic fibroblast-like synoviocytes in rats through PERK/TXNIP/NLRP3 signaling
por: Ding, Liang, et al.
Publicado: (2023)

Effects of Hypoxic Environment on Periodontal Tissue through the ROS/TXNIP/NLRP3 Inflammasome Pathway
por: Zhu, Rui, et al.
Publicado: (2022)

Expression and Mechanism of TXNIP/NLRP3 Inflammasome in Sciatic Nerve of Type 2 Diabetic Rats
por: Han, Le, et al.
Publicado: (2022)

NLRP3 inflammasome activation mediates radiation-induced pyroptosis in bone marrow-derived macrophages
por: Liu, Yan-gang, et al.
Publicado: (2017)

Gardnerella vaginalis induces NLRP3 inflammasome-mediated pyroptosis in macrophages and THP-1 monocytes
por: Xiang, Nan, et al.
Publicado: (2021)

The mechanisms of NLRP3 inflammasome/pyroptosis activation and their role in diabetic retinopathy
por: Zheng, Xiaoqin, et al.
Publicado: (2023)

NLRP3 inflammasome activation is involved in manganese-induced immunotoxicity: Mn activates macrophage NLRP3 inflammasome
por: Ji, Jing, et al.
Publicado: (2021)

Ethanol Augments Monosodium Urate-Induced NLRP3 Inflammasome Activation via Regulation of AhR and TXNIP in Human Macrophages
por: Kim, Seong-Kyu, et al.
Publicado: (2020)

N-Lobe of TXNIP Is Critical in the Allosteric Regulation of NLRP3 via TXNIP Binding
por: Cheng, Fengyu, et al.
Publicado: (2022)

Irisin suppresses pancreatic β cell pyroptosis in T2DM by inhibiting the NLRP3-GSDMD pathway and activating the Nrf2-TrX/TXNIP signaling axis
por: Li, Tianrong, et al.
Publicado: (2023)

High Glucose and Lipopolysaccharide Prime NLRP3 Inflammasome via ROS/TXNIP Pathway in Mesangial Cells
por: Feng, Hong, et al.
Publicado: (2016)

Honokiol antagonizes doxorubicin-induced cardiomyocyte senescence by inhibiting TXNIP-mediated NLRP3 inflammasome activation
por: Huang, Pian-Pian, et al.
Publicado: (2020)

SIRT1 Inhibits High Glucose–Induced TXNIP/NLRP3 Inflammasome Activation and Cataract Formation
por: Lian, Lili, et al.
Publicado: (2023)

Propofol directly induces caspase-1-dependent macrophage pyroptosis through the NLRP3-ASC inflammasome
por: Sun, Lingbin, et al.
Publicado: (2019)

miRNA-23a/CXCR4 regulates neuropathic pain via directly targeting TXNIP/NLRP3 inflammasome axis
por: Pan, Zhiqiang, et al.
Publicado: (2018)

NADPH Oxidase-Mediated Testicular Oxidative Imbalance Regulates the TXNIP/NLRP3 Inflammasome Axis Activation after Ischemia Reperfusion Injury
por: Almarzouq, Duaah, et al.
Publicado: (2023)

Cathepsin B Is Required for NLRP3 Inflammasome Activation in Macrophages, Through NLRP3 Interaction
por: Chevriaux, Angélique, et al.
Publicado: (2020)

Unraveling the Pathogenesis of MDS: The NLRP3 Inflammasome and Pyroptosis Drive the MDS Phenotype
por: Sallman, David A., et al.
Publicado: (2016)

Salidroside Ameliorates Alzheimer's Disease by Targeting NLRP3 Inflammasome-Mediated Pyroptosis
por: Cai, Yawen, et al.
Publicado: (2022)

NLRP3 inflammasome activation mediates sleep deprivation-induced pyroptosis in mice
por: Fan, Kun, et al.
Publicado: (2021)

Chloride sensing by WNK1 regulates NLRP3 inflammasome activation and pyroptosis
por: Mayes-Hopfinger, Lindsey, et al.
Publicado: (2021)

NLRP3 Inflammasome/Pyroptosis: A Key Driving Force in Diabetic Cardiomyopathy
por: Zhang, Lixia, et al.
Publicado: (2022)

Aerobic exercise alleviates pyroptosis-related diseases by regulating NLRP3 inflammasome
por: Hu, Shujuan, et al.
Publicado: (2022)

Role of TXNIP/NLRP3 in sepsis-induced myocardial dysfunction
por: Yang, Chun, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_8a290s2s4r3n1ap050h0mrds8m