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A single amino acid mutation in the mouse MEIG1 protein disrupts a cargo transport system necessary for sperm formation

Mammalian spermatogenesis is a highly coordinated process that requires cooperation between specific proteins to coordinate diverse biological functions. For example, mouse Parkin coregulated gene (PACRG) recruits meiosis-expressed gene 1 (MEIG1) to the manchette during normal spermiogenesis. Here w...

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Detalles Bibliográficos
Autores principales: Li, Wei, Huang, Qian, Zhang, Ling, Liu, Hong, Zhang, David, Yuan, Shuo, Yap, Yitian, Qu, Wei, Shiang, Rita, Song, Shizheng, Hess, Rex A., Zhang, Zhibing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592874/
https://www.ncbi.nlm.nih.gov/pubmed/34673028
http://dx.doi.org/10.1016/j.jbc.2021.101312