Naturally occurring cancer-associated mutations disrupt oligomerization and activity of protein arginine methyltransferase 1 (PRMT1)

Protein arginine methylation is a posttranslational modification catalyzed by the protein arginine methyltransferase (PRMT) enzyme family. Dysregulated protein arginine methylation is linked to cancer and a variety of other human diseases. PRMT1 is the predominant PRMT isoform in mammalian cells and...

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Detalles Bibliográficos
Autores principales: Price, Owen M., Thakur, Abhishek, Ortolano, Ariana, Towne, Arianna, Velez, Caroline, Acevedo, Orlando, Hevel, Joan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592882/
https://www.ncbi.nlm.nih.gov/pubmed/34688662
http://dx.doi.org/10.1016/j.jbc.2021.101336

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592882/
https://www.ncbi.nlm.nih.gov/pubmed/34688662
http://dx.doi.org/10.1016/j.jbc.2021.101336

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