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The BET bromodomain inhibitor ZEN-3365 targets the Hedgehog signaling pathway in acute myeloid leukemia
Modern cancer therapies increased the survival rates of acute myeloid leukemia (AML) patients tremendously. However, the complexity of the disease and the identification of new targets require the adaptation of treatment protocols to reduce side effects and increase benefit for the patients. One key...
Autores principales: | Wellbrock, Jasmin, Behrmann, Lena, Muschhammer, Jana, Modemann, Franziska, Khoury, Kais, Brauneck, Franziska, Bokemeyer, Carsten, Campeau, Eric, Fiedler, Walter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592969/ https://www.ncbi.nlm.nih.gov/pubmed/34333666 http://dx.doi.org/10.1007/s00277-021-04602-z |
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