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Red blood cell transfusion induces abnormal HIF-1α response to cytokine storm after adult cardiac surgery
Patients undergoing cardiac surgery develop a marked postoperative systemic inflammatory response. Blood transfusion may contribute to disruption of homeostasis in these patients. We sought to evaluate the impact of blood transfusion on serum interleukin-6 (IL-6), hypoxia induced factor-1 alpha (HIF...
Autores principales: | Viikinkoski, Emma, Jalkanen, Juho, Gunn, Jarmo, Vasankari, Tuija, Lehto, Joonas, Valtonen, Mika, Biancari, Fausto, Jalkanen, Sirpa, Airaksinen, K. E. Juhani, Hollmén, Maija, Kiviniemi, Tuomas O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592994/ https://www.ncbi.nlm.nih.gov/pubmed/34782683 http://dx.doi.org/10.1038/s41598-021-01695-4 |
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