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Red blood cell transfusion induces abnormal HIF-1α response to cytokine storm after adult cardiac surgery

Patients undergoing cardiac surgery develop a marked postoperative systemic inflammatory response. Blood transfusion may contribute to disruption of homeostasis in these patients. We sought to evaluate the impact of blood transfusion on serum interleukin-6 (IL-6), hypoxia induced factor-1 alpha (HIF...

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Detalles Bibliográficos
Autores principales: Viikinkoski, Emma, Jalkanen, Juho, Gunn, Jarmo, Vasankari, Tuija, Lehto, Joonas, Valtonen, Mika, Biancari, Fausto, Jalkanen, Sirpa, Airaksinen, K. E. Juhani, Hollmén, Maija, Kiviniemi, Tuomas O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592994/
https://www.ncbi.nlm.nih.gov/pubmed/34782683
http://dx.doi.org/10.1038/s41598-021-01695-4

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