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Topoisomerase II alpha inhibition can overcome taxane-resistant prostate cancer through DNA repair pathways

Cabazitaxel (CBZ) is approved for the treatment of docetaxel-resistant castration-resistant prostate cancer (CRPC). However, its efficacy against CRPC is limited, and there are no effective treatments for CBZ-resistant CRPC. This study explored the optimal treatment for CRPC in the post-cabazitaxel...

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Detalles Bibliográficos
Autores principales:	Hongo, Hiroshi, Kosaka, Takeo, Suzuki, Yoko, Mikami, Shuji, Fukada, Junichi, Oya, Mototsugu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593019/ https://www.ncbi.nlm.nih.gov/pubmed/34782700 http://dx.doi.org/10.1038/s41598-021-01697-2

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