Interaction of Spike protein and lipid membrane of SARS-CoV-2 with Ursodeoxycholic acid, an in-silico analysis

Numerous repositioned drugs have been sought to decrease the severity of SARS-CoV-2 infection. It is known that among its physicochemical properties, Ursodeoxycholic Acid (UDCA) has a reduction in surface tension and cholesterol solubilization, it has also been used to treat cholesterol gallstones a...

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Detalles Bibliográficos
Autores principales: Rodal Canales, Francisco Javier, Pérez-Campos Mayoral, Laura, Hernández-Huerta, María Teresa, Sánchez Navarro, Luis Manuel, Matias-Cervantes, Carlos Alberto, Martínez Cruz, Margarito, Cruz Parada, Eli, Zenteno, Edgar, Ramos-Martínez, Edgar Gustavo, Pérez-Campos Mayoral, Eduardo, Romero Díaz, Carlos, Pérez-Campos, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593036/
https://www.ncbi.nlm.nih.gov/pubmed/34782703
http://dx.doi.org/10.1038/s41598-021-01705-5

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