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Toxin secretion and trafficking by Mycobacterium tuberculosis

The tuberculosis necrotizing toxin (TNT) is the major cytotoxicity factor of Mycobacterium tuberculosis (Mtb) in macrophages. TNT is the C-terminal domain of the outer membrane protein CpnT and gains access to the cytosol to kill macrophages infected with Mtb. However, molecular mechanisms of TNT se...

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Detalles Bibliográficos
Autores principales:	Pajuelo, David, Tak, Uday, Zhang, Lei, Danilchanka, Olga, Tischler, Anna D., Niederweis, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593097/ https://www.ncbi.nlm.nih.gov/pubmed/34782620 http://dx.doi.org/10.1038/s41467-021-26925-1

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