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Untangling the clinicopathological significance of MRE11-RAD50-NBS1 complex in sporadic breast cancers

The MRE11–RAD50–NBS1 (MRN) complex is critical for genomic stability. Although germline mutations in MRN may increase breast cancer susceptibility, such mutations are extremely rare. Here, we have conducted a comprehensive clinicopathological study of MRN in sporadic breast cancers. We have protein...

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Detalles Bibliográficos
Autores principales:	Alblihy, Adel, Shoqafi, Ahmed, Toss, Michael S., Algethami, Mashael, Harris, Anna E., Jeyapalan, Jennie N., Abdel-Fatah, Tarek, Servante, Juliette, Chan, Stephen Y. T., Green, Andrew, Mongan, Nigel P., Rakha, Emad A., Madhusudan, Srinivasan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593132/ https://www.ncbi.nlm.nih.gov/pubmed/34782604 http://dx.doi.org/10.1038/s41523-021-00350-5

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