Cargando…

Bi-directional ribosome scanning controls the stringency of start codon selection

The fidelity of start codon recognition by ribosomes is paramount during protein synthesis. The current knowledge of eukaryotic translation initiation implies unidirectional 5ʹ→3ʹ migration of the pre-initiation complex (PIC) along the 5ʹ UTR. In probing translation initiation from ultra-short 5ʹ UT...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gu, Yifei, Mao, Yuanhui, Jia, Longfei, Dong, Leiming, Qian, Shu-Bing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593136/ https://www.ncbi.nlm.nih.gov/pubmed/34782646 http://dx.doi.org/10.1038/s41467-021-26923-3

Ejemplares similares

Translational regulation by uORFs and start codon selection stringency
por: Dever, Thomas E., et al.
Publicado: (2023)

Stringency of start codon selection modulates autoregulation of translation initiation factor eIF5
por: Loughran, Gary, et al.
Publicado: (2012)

Translational autoregulation of BZW1 and BZW2 expression by modulating the stringency of start codon selection
por: Loughran, Gary, et al.
Publicado: (2018)

Evolutionarily conserved inhibitory uORFs sensitize Hox mRNA translation to start codon selection stringency
por: Ivanov, Ivaylo P., et al.
Publicado: (2022)

Relaxed initiation pausing of ribosomes drives oncogenic translation
por: Dong, Leiming, et al.
Publicado: (2021)

Selection of start codon during mRNA scanning in eukaryotic translation initiation
por: Basu, Ipsita, et al.
Publicado: (2022)

Suppression of Ribosomal Pausing by eIF5A Is Necessary to Maintain the Fidelity of Start Codon Selection
por: Manjunath, Hema, et al.
Publicado: (2019)

Human SAMD9 is a poxvirus-activatable anticodon nuclease inhibiting codon-specific protein synthesis
por: Zhang, Fushun, et al.
Publicado: (2023)

Why is start codon selection so precise in eukaryotes?
por: Asano, Katsura
Publicado: (2014)

Codon optimality controls differential mRNA translation during amino acid starvation
por: Saikia, Mridusmita, et al.
Publicado: (2016)

Selection on start codons in prokaryotes and potential compensatory nucleotide substitutions
por: Belinky, Frida, et al.
Publicado: (2017)

Negative selection and stringency modulation in phage-assisted constinuous evolution
por: Carlson, Jacob C., et al.
Publicado: (2014)

Pervasive downstream RNA hairpins dynamically dictate start-codon selection
por: Xiang, Yezi, et al.
Publicado: (2023)

Free energy landscape of RNA binding dynamics in start codon recognition by eukaryotic ribosomal pre-initiation complex
por: Kameda, Takeru, et al.
Publicado: (2021)

Pharmacogenetic Selection of Volunteers Increases Stringency of Bioequivalence Studies; The Case of Clopidogrel
por: Garcés-Eisele, J., et al.
Publicado: (2014)

Eighty routes to a ribonucleotide world; dispersion and stringency in the decisive selection
por: Yarus, Michael
Publicado: (2018)

The antibiotic Furvina® targets the P-site of 30S ribosomal subunits and inhibits translation initiation displaying start codon bias
por: Fabbretti, Attilio, et al.
Publicado: (2012)

Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition
por: Llácer, Jose Luis, et al.
Publicado: (2018)

Cryo-EM study of start codon selection during archaeal translation initiation
por: Coureux, Pierre-Damien, et al.
Publicado: (2016)

BiP/GRP78 Mediates ERAD Targeting of Proteins Produced by Membrane-Bound Ribosomes Stalled at the STOP-Codon
por: Cesaratto, Francesca, et al.
Publicado: (2019)

Trading Health for Wealth: The Effect of COVID-19 Response Stringency
por: Cross, Megan, et al.
Publicado: (2020)

Does Governance Quality Matter for the Selection of Policy Stringency to Fight COVID-19?
por: Wang, Yan
Publicado: (2022)

On Ribosome Load, Codon Bias and Protein Abundance
por: Klumpp, Stefan, et al.
Publicado: (2012)

Minigene-like inhibition of protein synthesis mediated by hungry codons near the start codon
por: Jacinto-Loeza, Eva, et al.
Publicado: (2008)

Proline codon pair selection determines ribosome pausing strength and translation efficiency in bacteria
por: Krafczyk, Ralph, et al.
Publicado: (2021)

A high-stringency blueprint of the human proteome
por: Adhikari, Subash, et al.
Publicado: (2020)

Ribosomal scanning past the primary initiation codon as a mechanism for expression of CTL epitopes encoded in alternative reading frames
Publicado: (1996)

Stringent Nucleotide Recognition by the Ribosome at the Middle Codon Position
por: Liu, Wei, et al.
Publicado: (2017)

Ribosome Fate during Decoding of UGA-Sec Codons
por: Copeland, Paul R., et al.
Publicado: (2021)

Principles of start codon recognition in eukaryotic translation initiation
por: Lind, Christoffer, et al.
Publicado: (2016)

Multi-stringency wash of partially hybridized 60-mer probes reveals that the stringency along the probe decreases with distance from the microarray surface
por: Poulsen, Lena, et al.
Publicado: (2008)

Ribosome profiling reveals ribosome stalling on tryptophan codons and ribosome queuing upon oxidative stress in fission yeast
por: Rubio, Angela, et al.
Publicado: (2020)

Cargo crowding contributes to sorting stringency in COPII vesicles
por: Gomez-Navarro, Natalia, et al.
Publicado: (2020)

Towards a More Particularist View of Rights’ Stringency
por: Rumbold, Benedict
Publicado: (2018)

Effects of single amino acid deficiency on mRNA translation are markedly different for methionine versus leucine
por: Mazor, Kevin M., et al.
Publicado: (2018)

m(6)A in mRNA coding regions promotes translation via the RNA helicase-containing YTHDC2
por: Mao, Yuanhui, et al.
Publicado: (2019)

When a ribosome encounters a premature termination codon
por: Hwang, Jungwook, et al.
Publicado: (2013)

Efficient translation initiation dictates codon usage at gene start
por: Bentele, Kajetan, et al.
Publicado: (2013)

Large-scale movement of eIF3 domains during translation initiation modulate start codon selection
por: Llácer, Jose L, et al.
Publicado: (2021)

CRISPR Start-Loss: A Novel and Practical Alternative for Gene Silencing through Base-Editing-Induced Start Codon Mutations
por: Chen, Siyu, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_93kum42bc1eltkrvvulg1nsjsp