In-Depth Molecular Characterization of Neovascular Membranes Suggests a Role for Hyalocyte-to-Myofibroblast Transdifferentiation in Proliferative Diabetic Retinopathy

BACKGROUND: Retinal neovascularization (RNV) membranes can lead to a tractional retinal detachment, the primary reason for severe vision loss in end-stage disease proliferative diabetic retinopathy (PDR). The aim of this study was to characterize the molecular, cellular and immunological features of...

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Detalles Bibliográficos
Autores principales: Boneva, Stefaniya Konstantinova, Wolf, Julian, Hajdú, Rozina Ida, Prinz, Gabriele, Salié, Henrike, Schlecht, Anja, Killmer, Saskia, Laich, Yannik, Faatz, Henrik, Lommatzsch, Albrecht, Busch, Martin, Bucher, Felicitas, Stahl, Andreas, Böhringer, Daniel, Bengsch, Bertram, Schlunck, Günther, Agostini, Hansjürgen, Lange, Clemens A. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593213/
https://www.ncbi.nlm.nih.gov/pubmed/34795670
http://dx.doi.org/10.3389/fimmu.2021.757607

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