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Human Liver Stem Cell-Derived Extracellular Vesicles Target Hepatic Stellate Cells and Attenuate Their Pro-fibrotic Phenotype

Liver fibrosis occurs in response to chronic liver injury and is characterized by an excessive deposition of extracellular matrix. Activated hepatic stellate cells are primarily responsible for this process. A possible strategy to counteract the development of hepatic fibrosis could be the reversion...

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Detalles Bibliográficos
Autores principales: Chiabotto, Giulia, Ceccotti, Elena, Tapparo, Marta, Camussi, Giovanni, Bruno, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593217/
https://www.ncbi.nlm.nih.gov/pubmed/34796180
http://dx.doi.org/10.3389/fcell.2021.777462