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Human Liver Stem Cell-Derived Extracellular Vesicles Target Hepatic Stellate Cells and Attenuate Their Pro-fibrotic Phenotype
Liver fibrosis occurs in response to chronic liver injury and is characterized by an excessive deposition of extracellular matrix. Activated hepatic stellate cells are primarily responsible for this process. A possible strategy to counteract the development of hepatic fibrosis could be the reversion...
Autores principales: | Chiabotto, Giulia, Ceccotti, Elena, Tapparo, Marta, Camussi, Giovanni, Bruno, Stefania |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593217/ https://www.ncbi.nlm.nih.gov/pubmed/34796180 http://dx.doi.org/10.3389/fcell.2021.777462 |
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