Cargando…

Chinese Herbal Preparation SaiLuoTong Alleviates Brain Ischemia via Nrf2 Antioxidation Pathway–Dependent Cerebral Microvascular Protection

Stroke is one of the most devastating diseases worldwide. The Chinese herbal preparation SaiLuoTong (SLT) capsule showed outstanding therapeutic effects on stroke and its sequelae. The aim of this study was to further elucidate its therapeutic mechanism. We duplicated a permanent cerebral ischemia m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fan, Xiao-Di, Yao, Ming-Jiang, Yang, Bin, Han, Xiao, Zhang, Ye-Hao, Wang, Guang-Rui, Li, Peng, Xu, Li, Liu, Jian-Xun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593255/ https://www.ncbi.nlm.nih.gov/pubmed/34795584 http://dx.doi.org/10.3389/fphar.2021.748568

Ejemplares similares

Efficacy and safety of the compound Chinese medicine SaiLuoTong in vascular dementia: A randomized clinical trial
por: Jia, Jianping, et al.
Publicado: (2018)

A pilot randomized controlled trial of WeiNaoKang (SaiLuoTong) in treating vascular dementia
por: Liu, Junguang, et al.
Publicado: (2022)

A randomized, double‐blind, placebo‐controlled, parallel‐group 12‐week pilot phase II trial of SaiLuoTong (SLT) for cognitive function in older adults with mild cognitive impairment
por: Steiner‐Lim, Genevieve Z., et al.
Publicado: (2023)

Luo Tong Formula Alleviates Diabetic Retinopathy in Rats Through Micro-200b Target
por: Pang, Bing, et al.
Publicado: (2020)

Wen-Shen-Tong-Luo-Zhi-Tong Decoction regulates bone–fat balance in osteoporosis by adipocyte-derived exosomes
por: Wang, Lining, et al.
Publicado: (2023)

Protective effects of a compound herbal extract (Tong Xin Luo) on free fatty acid induced endothelial injury: Implications of antioxidant system
por: Zhang, Lin, et al.
Publicado: (2008)

Huo Xue Tong Luo capsule, a vasoactive herbal formula prevents progression of asymptomatic osteonecrosis of femoral head: A prospective study
por: Wei, Qiu-Shi, et al.
Publicado: (2018)

Chronic Administration of Anti-Stroke Herbal Medicine TongLuoJiuNao Reduces Amyloidogenic Processing of Amyloid Precursor Protein in a Mouse Model of Alzheimer’s Disease
por: He, Ping, et al.
Publicado: (2013)

Luo Tong formula attenuates retinal inflammation in diabetic rats via inhibition of the p38MAPK/NF-κB pathway
por: Pang, Bing, et al.
Publicado: (2020)

Study on efficacy and safety of Tong-luo Qu-tong plaster treatment for knee osteoarthritis: study protocol for a randomized, double-blind, parallel positive controlled, multi-center clinical trial
por: Xu, Bao-ping, et al.
Publicado: (2019)

An Integrated Approach Based on Network Analysis Combined With Experimental Verification Reveals PI3K/Akt/Nrf2 Signaling Is an Important Way for the Anti-Myocardial Ischemia Activity of Yi-Qi-Tong-Luo Capsule
por: Duan, Huxinyue, et al.
Publicado: (2022)

Wen-Luo-Tong Decoction Attenuates Paclitaxel-Induced Peripheral Neuropathy by Regulating Linoleic Acid and Glycerophospholipid Metabolism Pathways
por: Wu, Fei-ze, et al.
Publicado: (2018)

Wen-Luo-Tong Prevents Glial Activation and Nociceptive Sensitization in a Rat Model of Oxaliplatin-Induced Neuropathic Pain
por: Deng, Bo, et al.
Publicado: (2016)

Tu sais quoi?!
por: Dolidon, Annabelle, et al.
Publicado: (2012)

FuZhengHuaYuJiangZhuTongLuoFang Prescription Modulates Gut Microbiota and Gut-Derived Metabolites in UUO Rats
por: Chen, Ziwei, et al.
Publicado: (2022)

Exploration of the mechanisms underlying the beneficial effect of Luo Tong formula on retinal function in diabetic rats via the “gut microbiota–inflammation–retina” axis
por: Di, Sha, et al.
Publicado: (2022)

BaoShenTongLuo formula protects against podocyte injury by regulating AMPK-mediated mitochondrial biogenesis in diabetic kidney disease
por: Guo, Yifan, et al.
Publicado: (2023)

Shen-Hong-Tong-Luo Formula Attenuates Macrophage Inflammation and Lipid Accumulation through the Activation of the PPAR-γ/LXR-α/ABCA1 Pathway
por: Zhang, Zepeng, et al.
Publicado: (2020)

Network Pharmacology and Molecular Docking Study on the Potential Mechanism of Yi-Qi-Huo-Xue-Tong-Luo Formula in Treating Diabetic Peripheral Neuropathy
por: Lin, Yixuan, et al.
Publicado: (2021)

Sailuotong Capsule Prevents the Cerebral Ischaemia-Induced Neuroinflammation and Impairment of Recognition Memory through Inhibition of LCN2 Expression
por: Zhang, Yehao, et al.
Publicado: (2019)

Sai Baba y el psiquiatra /
por: Sandweiss, Samuel H.
Publicado: (1979)

Morroniside Improves Microvascular Functional Integrity of the Neurovascular Unit after Cerebral Ischemia
por: Sun, Fang-Ling, et al.
Publicado: (2014)

Endothelium-Independent Vasodilatory Effect of Sailuotong (SLT) on Rat Isolated Tail Artery
por: Yeon, S. Y., et al.
Publicado: (2020)

Response to Wang and Luo
por: Rehmsmeier, Marc
Publicado: (2012)

Protection of Tong-Sai-Mai Decoction against Apoptosis Induced by H(2)O(2) in PC12 Cells: Mechanisms via Bcl-2-Mitochondria-ROS-INOS Pathway
por: Lee, Maxwell Kim Kit, et al.
Publicado: (2014)

Tong Luo Jiu Nao ameliorates Aβ(1–40)-induced cognitive impairment on adaptive behavior learning by modulating ERK/CaMKII/CREB signaling in the hippocampus
por: Shi, Zhe, et al.
Publicado: (2015)

An Integrative Platform of TCM Network Pharmacology and Its Application on a Herbal Formula, Qing-Luo-Yin
por: Zhang, Bo, et al.
Publicado: (2013)

A multicenter, randomized, double-blind, placebo-controlled trial evaluating the efficacy and safety of Tong Luo Hua Shi capsule, a modernized Tibetan medicine, in patients with rheumatoid arthritis
por: Liu, Wei, et al.
Publicado: (2016)

Effectiveness of Traditional Chinese Medicine Compound JieDuTongLuoShengJin Granules Treatment in Primary Sjögren's Syndrome: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial
por: Li, Ben, et al.
Publicado: (2017)

SAI Intelligent Systems Conference (IntelliSys) 2015
por: Bi, Yaxin, et al.
Publicado: (2016)

Development and validation of a stock addiction inventory (SAI)
por: Youn, HyunChul, et al.
Publicado: (2016)

Procyanidins Alleviated Cerebral Ischemia/Reperfusion Injury by Inhibiting Ferroptosis via the Nrf2/HO-1 Signaling Pathway
por: Chen, Lei, et al.
Publicado: (2023)

The Therapeutic Effect of Huo Xue Tong Luo Capsules in Association Research Circulation Osseous (ARCO) Stage II Osteonecrosis of the Femoral Head: A Clinical Study With an Average Follow-up Period of 7.95 Years
por: He, Xiao-Ming, et al.
Publicado: (2021)

Shi's Yi-Qi Bu-Shen Tong-Luo decoction combined with manipulation in the management of wrist stiffness after distal radius fracture: Study protocol clinical trial (SPIRIT Compliant)
por: Wu, Hai-Yang, et al.
Publicado: (2020)

Ulinastatin alleviates cerebral ischemia-reperfusion injury in rats by activating the Nrf-2/HO-1 signaling pathway
por: Cui, Lei, et al.
Publicado: (2020)

Study protocol for a phase III randomised controlled trial of Sailuotong (SLT) for vascular dementia and Alzheimer’s disease with cerebrovascular disease
por: Karamacoska, Diana, et al.
Publicado: (2023)

Corrigendum: The Therapeutic Effect of Huo Xue Tong Luo Capsules in Association Research Circulation Osseous (ARCO) Stage II Osteonecrosis of the Femoral Head: A Clinical Study With an Average Follow-up Period of 7.95 Years
por: He, Xiao-Ming, et al.
Publicado: (2022)

The effect of Sailuotong (SLT) on neurocognitive and cardiovascular function in healthy adults: a randomised, double-blind, placebo controlled crossover pilot trial
por: Steiner, Genevieve Z., et al.
Publicado: (2016)

Astragaloside IV Alleviates Cerebral Ischemia-Reperfusion Injury through NLRP3 Inflammasome-Mediated Pyroptosis Inhibition via Activating Nrf2
por: Xiao, Lan, et al.
Publicado: (2021)

A Metabonomics Investigation into the Therapeutic Effects of BuChang NaoXinTong Capsules on Reversing the Amino Acid-Protein Interaction Network of Cerebral Ischemia
por: Xu, Jing, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_cvf8srlk81oriq9v7i3qmfqt4u