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A successful treatment with intravenous lipid emulsion therapy in a child with verapamil poisoning

In recent years, intravenous lipid emulsion therapy (ILE) was used for lipophilic drug intoxications, and successful results were obtained. In the literature, there is a small number of reported cases about verapamil intoxication and ILE therapy in the pediatric age group. We used ILE therapy in a 1...

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Detalles Bibliográficos
Autores principales: Havan, Merve, Kendirli, Tanıl, Özcan, Serhan, Doğan, Melih Timuçin, Yiğit, Ahmet Onur, Uçar, Tayfun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593422/
https://www.ncbi.nlm.nih.gov/pubmed/34849436
http://dx.doi.org/10.4103/2452-2473.329626
Descripción
Sumario:In recent years, intravenous lipid emulsion therapy (ILE) was used for lipophilic drug intoxications, and successful results were obtained. In the literature, there is a small number of reported cases about verapamil intoxication and ILE therapy in the pediatric age group. We used ILE therapy in a 14-year-old girl with verapamil intoxication in the 2(nd) h of the pediatric intensive care unit stay, before using traditional treatments such as glucagon and hyperinsulinemic euglycemia. She had resistant bradycardia and hypotension which was unresponsive to inotropic agents and a successful result was obtained after using ILE treatment. We believe our report may contribute to the early use of ILE therapy for toxicity with calcium channel blockers such as verapamil in pediatric patients.