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A successful treatment with intravenous lipid emulsion therapy in a child with verapamil poisoning

In recent years, intravenous lipid emulsion therapy (ILE) was used for lipophilic drug intoxications, and successful results were obtained. In the literature, there is a small number of reported cases about verapamil intoxication and ILE therapy in the pediatric age group. We used ILE therapy in a 1...

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Autores principales: Havan, Merve, Kendirli, Tanıl, Özcan, Serhan, Doğan, Melih Timuçin, Yiğit, Ahmet Onur, Uçar, Tayfun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593422/
https://www.ncbi.nlm.nih.gov/pubmed/34849436
http://dx.doi.org/10.4103/2452-2473.329626
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author Havan, Merve
Kendirli, Tanıl
Özcan, Serhan
Doğan, Melih Timuçin
Yiğit, Ahmet Onur
Uçar, Tayfun
author_facet Havan, Merve
Kendirli, Tanıl
Özcan, Serhan
Doğan, Melih Timuçin
Yiğit, Ahmet Onur
Uçar, Tayfun
author_sort Havan, Merve
collection PubMed
description In recent years, intravenous lipid emulsion therapy (ILE) was used for lipophilic drug intoxications, and successful results were obtained. In the literature, there is a small number of reported cases about verapamil intoxication and ILE therapy in the pediatric age group. We used ILE therapy in a 14-year-old girl with verapamil intoxication in the 2(nd) h of the pediatric intensive care unit stay, before using traditional treatments such as glucagon and hyperinsulinemic euglycemia. She had resistant bradycardia and hypotension which was unresponsive to inotropic agents and a successful result was obtained after using ILE treatment. We believe our report may contribute to the early use of ILE therapy for toxicity with calcium channel blockers such as verapamil in pediatric patients.
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spelling pubmed-85934222021-11-29 A successful treatment with intravenous lipid emulsion therapy in a child with verapamil poisoning Havan, Merve Kendirli, Tanıl Özcan, Serhan Doğan, Melih Timuçin Yiğit, Ahmet Onur Uçar, Tayfun Turk J Emerg Med Case Report In recent years, intravenous lipid emulsion therapy (ILE) was used for lipophilic drug intoxications, and successful results were obtained. In the literature, there is a small number of reported cases about verapamil intoxication and ILE therapy in the pediatric age group. We used ILE therapy in a 14-year-old girl with verapamil intoxication in the 2(nd) h of the pediatric intensive care unit stay, before using traditional treatments such as glucagon and hyperinsulinemic euglycemia. She had resistant bradycardia and hypotension which was unresponsive to inotropic agents and a successful result was obtained after using ILE treatment. We believe our report may contribute to the early use of ILE therapy for toxicity with calcium channel blockers such as verapamil in pediatric patients. Wolters Kluwer - Medknow 2021-10-29 /pmc/articles/PMC8593422/ /pubmed/34849436 http://dx.doi.org/10.4103/2452-2473.329626 Text en Copyright: © 2021 Turkish Journal of Emergency Medicine https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Havan, Merve
Kendirli, Tanıl
Özcan, Serhan
Doğan, Melih Timuçin
Yiğit, Ahmet Onur
Uçar, Tayfun
A successful treatment with intravenous lipid emulsion therapy in a child with verapamil poisoning
title A successful treatment with intravenous lipid emulsion therapy in a child with verapamil poisoning
title_full A successful treatment with intravenous lipid emulsion therapy in a child with verapamil poisoning
title_fullStr A successful treatment with intravenous lipid emulsion therapy in a child with verapamil poisoning
title_full_unstemmed A successful treatment with intravenous lipid emulsion therapy in a child with verapamil poisoning
title_short A successful treatment with intravenous lipid emulsion therapy in a child with verapamil poisoning
title_sort successful treatment with intravenous lipid emulsion therapy in a child with verapamil poisoning
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593422/
https://www.ncbi.nlm.nih.gov/pubmed/34849436
http://dx.doi.org/10.4103/2452-2473.329626
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