Intravitreal Methotrexate

Intravitreal methotrexate (MTX) has been proven to be an effective treatment for various intraocular diseases. In this article, a comprehensive review was performed on intravitreal applications of methotrexate. Different aspects of the administration of intravitreal MTX for various clinical conditio...

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Detalles Bibliográficos
Autores principales: Abdi, Fatemeh, Mohammadi, S. Saeed, Falavarjani, Khalil Ghasemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PUBLISHED BY KNOWLEDGE E 2021
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593537/
https://www.ncbi.nlm.nih.gov/pubmed/34840688
http://dx.doi.org/10.18502/jovr.v16i4.9756
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author Abdi, Fatemeh
Mohammadi, S. Saeed
Falavarjani, Khalil Ghasemi
author_facet Abdi, Fatemeh
Mohammadi, S. Saeed
Falavarjani, Khalil Ghasemi
author_sort Abdi, Fatemeh
collection PubMed
description Intravitreal methotrexate (MTX) has been proven to be an effective treatment for various intraocular diseases. In this article, a comprehensive review was performed on intravitreal applications of methotrexate. Different aspects of the administration of intravitreal MTX for various clinical conditions such as intraocular tumors, proliferative vitreoretinopathy, diabetic retinopathy, age-related macular degeneration, and uveitis were reviewed and the adverse effects of intravitreal injection of MTX were discussed. The most common indications are intraocular lymphoma and uveitis. Other applications remain challenging and more studies are needed to establish the role of intravitreal MTX in the management of ocular diseases.
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spelling pubmed-85935372021-11-26 Intravitreal Methotrexate Abdi, Fatemeh Mohammadi, S. Saeed Falavarjani, Khalil Ghasemi J Ophthalmic Vis Res Review Article Intravitreal methotrexate (MTX) has been proven to be an effective treatment for various intraocular diseases. In this article, a comprehensive review was performed on intravitreal applications of methotrexate. Different aspects of the administration of intravitreal MTX for various clinical conditions such as intraocular tumors, proliferative vitreoretinopathy, diabetic retinopathy, age-related macular degeneration, and uveitis were reviewed and the adverse effects of intravitreal injection of MTX were discussed. The most common indications are intraocular lymphoma and uveitis. Other applications remain challenging and more studies are needed to establish the role of intravitreal MTX in the management of ocular diseases. PUBLISHED BY KNOWLEDGE E 2021-10-25 /pmc/articles/PMC8593537/ /pubmed/34840688 http://dx.doi.org/10.18502/jovr.v16i4.9756 Text en Copyright © 2021 Abdi et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Abdi, Fatemeh
Mohammadi, S. Saeed
Falavarjani, Khalil Ghasemi
Intravitreal Methotrexate
title Intravitreal Methotrexate
title_full Intravitreal Methotrexate
title_fullStr Intravitreal Methotrexate
title_full_unstemmed Intravitreal Methotrexate
title_short Intravitreal Methotrexate
title_sort intravitreal methotrexate
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593537/
https://www.ncbi.nlm.nih.gov/pubmed/34840688
http://dx.doi.org/10.18502/jovr.v16i4.9756
work_keys_str_mv AT abdifatemeh intravitrealmethotrexate
AT mohammadissaeed intravitrealmethotrexate
AT falavarjanikhalilghasemi intravitrealmethotrexate

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