Comparative analysis of the molecular mechanism of resistance to vapendavir across a panel of picornavirus species

Vapendavir is a rhino/enterovirus inhibitor that targets a hydrophobic pocket in the viral capsid preventing the virus from entering the cell. We set out to study and compare the molecular mechanisms of resistance to vapendavir among clinically relevant Picornavirus species. To this end in vitro res...

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Detalles Bibliográficos
Autores principales: Lanko, Kristina, Sun, Liang, Froeyen, Mathy, Leyssen, Pieter, Delang, Leen, Mirabelli, Carmen, Neyts, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593553/
https://www.ncbi.nlm.nih.gov/pubmed/34517053
http://dx.doi.org/10.1016/j.antiviral.2021.105177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593553/
https://www.ncbi.nlm.nih.gov/pubmed/34517053
http://dx.doi.org/10.1016/j.antiviral.2021.105177

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