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Comparative analysis of the molecular mechanism of resistance to vapendavir across a panel of picornavirus species
Vapendavir is a rhino/enterovirus inhibitor that targets a hydrophobic pocket in the viral capsid preventing the virus from entering the cell. We set out to study and compare the molecular mechanisms of resistance to vapendavir among clinically relevant Picornavirus species. To this end in vitro res...
Autores principales: | Lanko, Kristina, Sun, Liang, Froeyen, Mathy, Leyssen, Pieter, Delang, Leen, Mirabelli, Carmen, Neyts, Johan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593553/ https://www.ncbi.nlm.nih.gov/pubmed/34517053 http://dx.doi.org/10.1016/j.antiviral.2021.105177 |
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