CD95/Fas protects triple negative breast cancer from anti-tumor activity of NK cells

The apoptosis inducing receptor CD95/Fas has multiple tumorigenic activities. In different genetically engineered mouse models tumor-expressed CD95 was shown to be critical for cell growth. Using a combination of immune-deficient and immune-competent mouse models, we now establish that loss of CD95...

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Detalles Bibliográficos
Autores principales: Qadir, Abdul S., Guégan, Jean Philippe, Ginestier, Christophe, Chaibi, Assia, Bessede, Alban, Charafe-Jauffret, Emmanuelle, Macario, Manon, Lavoué, Vincent, Rouge, Thibault de la Motte, Law, Calvin, Vilker, Jacob, Wang, Hongbin, Stroup, Emily, Schipma, Matthew J., Bridgeman, Bryan, Murmann, Andrea E., Ji, Zhe, Legembre, Patrick, Peter, Marcus E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593563/
https://www.ncbi.nlm.nih.gov/pubmed/34816102
http://dx.doi.org/10.1016/j.isci.2021.103348

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