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SYK-3BP2 Pathway Activity in Parenchymal and Myeloid Cells Is a Key Pathogenic Factor in Metabolic Steatohepatitis

BACKGROUND & AIMS: Spleen tyrosine kinase (SYK) signaling pathway regulates critical processes in innate immunity, but its role in parenchymal cells remains elusive in chronic liver diseases. We investigate the relative contribution of SYK and its substrate c-Abl Src homology 3 domain-binding pr...

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Detalles Bibliográficos
Autores principales:	Luci, Carmelo, Vieira, Elodie, Bourinet, Manon, Rousseau, Déborah, Bonnafous, Stéphanie, Patouraux, Stéphanie, Lefevre, Lauren, Larbret, Frederic, Prod’homme, Virginie, Iannelli, Antonio, Tran, Albert, Anty, Rodolphe, Bailly-Maitre, Béatrice, Deckert, Marcel, Gual, Philippe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593618/ https://www.ncbi.nlm.nih.gov/pubmed/34411785 http://dx.doi.org/10.1016/j.jcmgh.2021.08.004

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