Identification of p.Met215Ile mutation of the MC4R gene in a Moroccan woman with obesity

Screening the MC4R gene showed one rare mutation p.Met215Ile in a Moroccan patient with morbid obesity, which leads to a change in the protein structure. The analysis of MC4R variants may be useful for future therapeutic approaches.

Detalles Bibliográficos
Autores principales: El Fessikh, Meriem, Belghiti, Hakim, Elkarhat, Zouhair, Guerinech, Hassania, Dakka, Nadia, El Baghdadi, Jamila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593808/
https://www.ncbi.nlm.nih.gov/pubmed/34815872
http://dx.doi.org/10.1002/ccr3.5059
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author El Fessikh, Meriem
Belghiti, Hakim
Elkarhat, Zouhair
Guerinech, Hassania
Dakka, Nadia
El Baghdadi, Jamila
author_facet El Fessikh, Meriem
Belghiti, Hakim
Elkarhat, Zouhair
Guerinech, Hassania
Dakka, Nadia
El Baghdadi, Jamila
author_sort El Fessikh, Meriem
collection PubMed
description Screening the MC4R gene showed one rare mutation p.Met215Ile in a Moroccan patient with morbid obesity, which leads to a change in the protein structure. The analysis of MC4R variants may be useful for future therapeutic approaches.
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spelling pubmed-85938082021-11-22 Identification of p.Met215Ile mutation of the MC4R gene in a Moroccan woman with obesity El Fessikh, Meriem Belghiti, Hakim Elkarhat, Zouhair Guerinech, Hassania Dakka, Nadia El Baghdadi, Jamila Clin Case Rep Case Report Screening the MC4R gene showed one rare mutation p.Met215Ile in a Moroccan patient with morbid obesity, which leads to a change in the protein structure. The analysis of MC4R variants may be useful for future therapeutic approaches. John Wiley and Sons Inc. 2021-11-16 /pmc/articles/PMC8593808/ /pubmed/34815872 http://dx.doi.org/10.1002/ccr3.5059 Text en © 2021 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Report
El Fessikh, Meriem
Belghiti, Hakim
Elkarhat, Zouhair
Guerinech, Hassania
Dakka, Nadia
El Baghdadi, Jamila
Identification of p.Met215Ile mutation of the MC4R gene in a Moroccan woman with obesity
title Identification of p.Met215Ile mutation of the MC4R gene in a Moroccan woman with obesity
title_full Identification of p.Met215Ile mutation of the MC4R gene in a Moroccan woman with obesity
title_fullStr Identification of p.Met215Ile mutation of the MC4R gene in a Moroccan woman with obesity
title_full_unstemmed Identification of p.Met215Ile mutation of the MC4R gene in a Moroccan woman with obesity
title_short Identification of p.Met215Ile mutation of the MC4R gene in a Moroccan woman with obesity
title_sort identification of p.met215ile mutation of the mc4r gene in a moroccan woman with obesity
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593808/
https://www.ncbi.nlm.nih.gov/pubmed/34815872
http://dx.doi.org/10.1002/ccr3.5059
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