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Post Partum Death in a Patient Diagnosed With COVID-19

Background: There are few case reports describing maternal mortality and intensive care of the pregnant patient with COVID-19 infection. Case: A 27-year-old patient at 34 weeks of gestation was admitted for the evaluation of cough, fever, tachypnea, and oligohydramnios. The day of admission she unde...

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Autores principales: Sivevski, Atanas, Karadzova, Dafina, Davceva, Natasha, Aleksioska-Papestiev, Irena, Kadriu, Romir, Velickovic, Ivan, Markovic, Ivana, Pejcic, Nada, Baysinger, Curtis L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593966/
https://www.ncbi.nlm.nih.gov/pubmed/34816153
http://dx.doi.org/10.3389/fgwh.2020.567810
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author Sivevski, Atanas
Karadzova, Dafina
Davceva, Natasha
Aleksioska-Papestiev, Irena
Kadriu, Romir
Velickovic, Ivan
Markovic, Ivana
Pejcic, Nada
Baysinger, Curtis L.
author_facet Sivevski, Atanas
Karadzova, Dafina
Davceva, Natasha
Aleksioska-Papestiev, Irena
Kadriu, Romir
Velickovic, Ivan
Markovic, Ivana
Pejcic, Nada
Baysinger, Curtis L.
author_sort Sivevski, Atanas
collection PubMed
description Background: There are few case reports describing maternal mortality and intensive care of the pregnant patient with COVID-19 infection. Case: A 27-year-old patient at 34 weeks of gestation was admitted for the evaluation of cough, fever, tachypnea, and oligohydramnios. The day of admission she underwent cesarean delivery for a non-reassuring fetal heart rate tracing. Over the next 6 days her clinical condition deteriorated, she developed multi organ system failure, and died despite aggressive supportive care. Conclusion: Although mortality related to COVID-19 in pregnancy has been rarely reported to date, we describe a case of progressive clinical deterioration postpartum despite aggressive supportive care. Management strategies specific for pregnant women have not been developed. In timing delivery, the obstetrician must consider the possibility that the inflammatory response associated with CD may increase the risk for multiorgan system failure in parturients with COVID-19 while recognizing that risks to the fetus may be higher in patients with COVID-19 than in other critically ill parturients. Vertical transmission of infection to the neonate did not occur in our case and has not been demonstrated in other pregnancies with COVID-19 disease.
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spelling pubmed-85939662021-11-22 Post Partum Death in a Patient Diagnosed With COVID-19 Sivevski, Atanas Karadzova, Dafina Davceva, Natasha Aleksioska-Papestiev, Irena Kadriu, Romir Velickovic, Ivan Markovic, Ivana Pejcic, Nada Baysinger, Curtis L. Front Glob Womens Health Global Women's Health Background: There are few case reports describing maternal mortality and intensive care of the pregnant patient with COVID-19 infection. Case: A 27-year-old patient at 34 weeks of gestation was admitted for the evaluation of cough, fever, tachypnea, and oligohydramnios. The day of admission she underwent cesarean delivery for a non-reassuring fetal heart rate tracing. Over the next 6 days her clinical condition deteriorated, she developed multi organ system failure, and died despite aggressive supportive care. Conclusion: Although mortality related to COVID-19 in pregnancy has been rarely reported to date, we describe a case of progressive clinical deterioration postpartum despite aggressive supportive care. Management strategies specific for pregnant women have not been developed. In timing delivery, the obstetrician must consider the possibility that the inflammatory response associated with CD may increase the risk for multiorgan system failure in parturients with COVID-19 while recognizing that risks to the fetus may be higher in patients with COVID-19 than in other critically ill parturients. Vertical transmission of infection to the neonate did not occur in our case and has not been demonstrated in other pregnancies with COVID-19 disease. Frontiers Media S.A. 2020-09-24 /pmc/articles/PMC8593966/ /pubmed/34816153 http://dx.doi.org/10.3389/fgwh.2020.567810 Text en Copyright © 2020 Sivevski, Karadzova, Davceva, Aleksioska-Papestiev, Kadriu, Velickovic, Markovic, Pejcic and Baysinger. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Global Women's Health
Sivevski, Atanas
Karadzova, Dafina
Davceva, Natasha
Aleksioska-Papestiev, Irena
Kadriu, Romir
Velickovic, Ivan
Markovic, Ivana
Pejcic, Nada
Baysinger, Curtis L.
Post Partum Death in a Patient Diagnosed With COVID-19
title Post Partum Death in a Patient Diagnosed With COVID-19
title_full Post Partum Death in a Patient Diagnosed With COVID-19
title_fullStr Post Partum Death in a Patient Diagnosed With COVID-19
title_full_unstemmed Post Partum Death in a Patient Diagnosed With COVID-19
title_short Post Partum Death in a Patient Diagnosed With COVID-19
title_sort post partum death in a patient diagnosed with covid-19
topic Global Women's Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8593966/
https://www.ncbi.nlm.nih.gov/pubmed/34816153
http://dx.doi.org/10.3389/fgwh.2020.567810
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