DNA aptamers masking angiotensin converting enzyme 2 as an innovative way to treat SARS-CoV-2 pandemic

All the different coronavirus SARS-CoV-2 variants isolated so far share the same mechanism of infection mediated by the interaction of their spike (S) glycoprotein with specific residues on their cellular receptor: the angiotensin converting enzyme 2 (ACE2). Therefore, the steric hindrance on this c...

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Detalles Bibliográficos
Autores principales: Villa, Alessandro, Brunialti, Electra, Dellavedova, Jessica, Meda, Clara, Rebecchi, Monica, Conti, Matteo, Donnici, Lorena, De Francesco, Raffaele, Reggiani, Angelo, Lionetti, Vincenzo, Ciana, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594078/
https://www.ncbi.nlm.nih.gov/pubmed/34798263
http://dx.doi.org/10.1016/j.phrs.2021.105982

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