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A mouse model of neoadjuvant chemotherapy followed by interval cytoreductive surgery indicates impaired efficacy of perioperative cisplatin

BACKGROUND: Investigate the impact of interval cytoreductive surgery (ICS) on progression in an orthotopic mouse model of ovarian cancer and the impact of chemotherapy delivered at various timelines following surgery. METHODS: Luciferase-expressing ID8 murine ovarian cancer cells were implanted intr...

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Detalles Bibliográficos
Autores principales: Clark, Mitchell, Kollara, Alexandra, Brown, Theodore J., May, Taymaa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594094/
https://www.ncbi.nlm.nih.gov/pubmed/34784944
http://dx.doi.org/10.1186/s13048-021-00895-w

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