Knockdown of long noncoding RNA GAS5 reduces vascular smooth muscle cell apoptosis by inactivating EZH2-mediated RIG-I signaling pathway in abdominal aortic aneurysm

BACKGROUND: Abdominal aortic aneurysm (AAA), an irreversible cardiovascular disease prevalent in the artery, causes the increase of the aneurysm diameter over time, and is a fatal phenomenon inducing sidewall rupture. Long noncoding RNAs (lncRNAs) serve as promising biomarkers for AAA. In the presen...

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Detalles Bibliográficos
Autores principales: Le, Tianming, He, Xin, Huang, Jianhua, Liu, Shuai, Bai, Yang, Wu, Kemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594130/
https://www.ncbi.nlm.nih.gov/pubmed/34781960
http://dx.doi.org/10.1186/s12967-021-03023-w

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