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Prediction of anti-CD25 and 5-FU treatments efficacy for pancreatic cancer using a mathematical model

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease with rising incidence and with 5-years overall survival of less than 8%. PDAC creates an immune-suppressive tumor microenvironment to escape immune-mediated eradication. Regulatory T (Treg) cells and myeloid-derived suppr...

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Detalles Bibliográficos
Autores principales: Shafiekhani, Sajad, Dehghanbanadaki, Hojat, Fatemi, Azam Sadat, Rahbar, Sara, Hadjati, Jamshid, Jafari, Amir Homayoun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594222/
https://www.ncbi.nlm.nih.gov/pubmed/34781899
http://dx.doi.org/10.1186/s12885-021-08770-z