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Prediction of anti-CD25 and 5-FU treatments efficacy for pancreatic cancer using a mathematical model
BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal disease with rising incidence and with 5-years overall survival of less than 8%. PDAC creates an immune-suppressive tumor microenvironment to escape immune-mediated eradication. Regulatory T (Treg) cells and myeloid-derived suppr...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594222/ https://www.ncbi.nlm.nih.gov/pubmed/34781899 http://dx.doi.org/10.1186/s12885-021-08770-z |