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Biosynthesis and regulation of terpenoids from basidiomycetes: exploration of new research
Basidiomycetes, also known as club fungi, consist of a specific group of fungi. Basidiomycetes produce a large number of secondary metabolites, of which sesquiterpenoids, diterpenoids and triterpenoids are the primary components. However, these terpenoids tend to be present in low amounts, which mak...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594250/ https://www.ncbi.nlm.nih.gov/pubmed/34779947 http://dx.doi.org/10.1186/s13568-021-01304-7 |
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author | Wang, Qi Cao, Rui Zhang, Yuna Qi, Pengyan Wang, Lizhi Fang, Shiming |
author_facet | Wang, Qi Cao, Rui Zhang, Yuna Qi, Pengyan Wang, Lizhi Fang, Shiming |
author_sort | Wang, Qi |
collection | PubMed |
description | Basidiomycetes, also known as club fungi, consist of a specific group of fungi. Basidiomycetes produce a large number of secondary metabolites, of which sesquiterpenoids, diterpenoids and triterpenoids are the primary components. However, these terpenoids tend to be present in low amounts, which makes it difficult to meet application requirements. Terpenoid biosynthesis improves the quantity of these secondary metabolites. However, current understanding of the biosynthetic mechanism of terpenoids in basidiomycetes is insufficient. Therefore, this article reviews the latest research on the biosynthesis of terpenoids in basidiomycetes and summarizes the CYP450 involved in the biosynthesis of terpenoids in basidiomycetes. We also propose opportunities and challenges for chassis microbial heterologous production of terpenoids in basidiomycetes and provide a reference basis for the better development of basidiomycete engineering. |
format | Online Article Text |
id | pubmed-8594250 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-85942502021-12-02 Biosynthesis and regulation of terpenoids from basidiomycetes: exploration of new research Wang, Qi Cao, Rui Zhang, Yuna Qi, Pengyan Wang, Lizhi Fang, Shiming AMB Express Mini-Review Basidiomycetes, also known as club fungi, consist of a specific group of fungi. Basidiomycetes produce a large number of secondary metabolites, of which sesquiterpenoids, diterpenoids and triterpenoids are the primary components. However, these terpenoids tend to be present in low amounts, which makes it difficult to meet application requirements. Terpenoid biosynthesis improves the quantity of these secondary metabolites. However, current understanding of the biosynthetic mechanism of terpenoids in basidiomycetes is insufficient. Therefore, this article reviews the latest research on the biosynthesis of terpenoids in basidiomycetes and summarizes the CYP450 involved in the biosynthesis of terpenoids in basidiomycetes. We also propose opportunities and challenges for chassis microbial heterologous production of terpenoids in basidiomycetes and provide a reference basis for the better development of basidiomycete engineering. Springer Berlin Heidelberg 2021-11-15 /pmc/articles/PMC8594250/ /pubmed/34779947 http://dx.doi.org/10.1186/s13568-021-01304-7 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Mini-Review Wang, Qi Cao, Rui Zhang, Yuna Qi, Pengyan Wang, Lizhi Fang, Shiming Biosynthesis and regulation of terpenoids from basidiomycetes: exploration of new research |
title | Biosynthesis and regulation of terpenoids from basidiomycetes: exploration of new research |
title_full | Biosynthesis and regulation of terpenoids from basidiomycetes: exploration of new research |
title_fullStr | Biosynthesis and regulation of terpenoids from basidiomycetes: exploration of new research |
title_full_unstemmed | Biosynthesis and regulation of terpenoids from basidiomycetes: exploration of new research |
title_short | Biosynthesis and regulation of terpenoids from basidiomycetes: exploration of new research |
title_sort | biosynthesis and regulation of terpenoids from basidiomycetes: exploration of new research |
topic | Mini-Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594250/ https://www.ncbi.nlm.nih.gov/pubmed/34779947 http://dx.doi.org/10.1186/s13568-021-01304-7 |
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