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Eculizumab Pharmacokinetics and Pharmacodynamics in Patients With Generalized Myasthenia Gravis
Objective: To investigate the pharmacokinetics, pharmacodynamics, and exposure–response of the approved 900/1,200 mg dosing regimen for the terminal complement component 5 (C5) inhibitor eculizumab in patients with generalized myasthenia gravis (gMG). Methods: The analysis used data from 62 patients...
Autores principales: | Monteleone, Jonathan P. R., Gao, Xiang, Kleijn, Huub Jan, Bellanti, Francesco, Pelto, Ryan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594444/ https://www.ncbi.nlm.nih.gov/pubmed/34795626 http://dx.doi.org/10.3389/fneur.2021.696385 |
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