Sustained Post-Developmental T-Bet Expression Is Critical for the Maintenance of Type One Innate Lymphoid Cells In Vivo

Innate lymphoid cells (ILC) play a significant role in the intestinal immune response and T-bet(+) CD127(+) group 1 cells (ILC1) have been linked to the pathogenesis of human inflammatory bowel disease (IBD). However, the functional importance of ILC1 in the context of an intact adaptive immune resp...

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Detalles Bibliográficos
Autores principales: Schroeder, Jan-Hendrik, Roberts, Luke B., Meissl, Katrin, Lo, Jonathan W., Hromadová, Dominika, Hayes, Kelly, Zabinski, Tomasz, Read, Emily, Moreira Heliodoro, Catarina, Reis, Rita, Howard, Jane K., Grencis, Richard K., Neves, Joana F., Strobl, Birgit, Lord, Graham M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594445/
https://www.ncbi.nlm.nih.gov/pubmed/34795671
http://dx.doi.org/10.3389/fimmu.2021.760198

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