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Oral Manifestations of Early Syphilis in Adults: A Systematic Review of Case Reports and Series
Rapid emergence of syphilis and oral sexual behaviors has focused attention on oral syphilis, and published reports of cases with oral syphilis have increased in the recent decades. We performed a systematic literature review by searching articles from PubMed, EMBSE, and Google Scholar, looking for...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594522/ https://www.ncbi.nlm.nih.gov/pubmed/34433795 http://dx.doi.org/10.1097/OLQ.0000000000001538 |
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author | Zhou, Xiao Wu, Min-Zhi Jiang, Ting-Ting Chen, Xiang-Sheng |
author_facet | Zhou, Xiao Wu, Min-Zhi Jiang, Ting-Ting Chen, Xiang-Sheng |
author_sort | Zhou, Xiao |
collection | PubMed |
description | Rapid emergence of syphilis and oral sexual behaviors has focused attention on oral syphilis, and published reports of cases with oral syphilis have increased in the recent decades. We performed a systematic literature review by searching articles from PubMed, EMBSE, and Google Scholar, looking for case reports or series that would potentially have the clinical characteristics and outcomes for each individual case with oral syphilis. A total of 145 cases with the infection, from 95 studies, were identified to include in our review. Two main clinical phenotypes (ulcerative lesions and mucous patches) appeared to be of particular relevance to oral manifestations. A solitary ulcer was mostly manifested as the lesion of primary syphilis (91.7%) preferentially located on the upper lip, tongue, palate, and buccal mucosa. The most affected anatomical site in the patients with single location involved was the tongue (37.5%), followed by the lips (29.5%), palates (19.3%), and buccal mucosa (6.8%). It is concluded that oral syphilis has its predominant clinical phenotypes although it can manifest in diverse manners. |
format | Online Article Text |
id | pubmed-8594522 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-85945222021-11-19 Oral Manifestations of Early Syphilis in Adults: A Systematic Review of Case Reports and Series Zhou, Xiao Wu, Min-Zhi Jiang, Ting-Ting Chen, Xiang-Sheng Sex Transm Dis Reviews Rapid emergence of syphilis and oral sexual behaviors has focused attention on oral syphilis, and published reports of cases with oral syphilis have increased in the recent decades. We performed a systematic literature review by searching articles from PubMed, EMBSE, and Google Scholar, looking for case reports or series that would potentially have the clinical characteristics and outcomes for each individual case with oral syphilis. A total of 145 cases with the infection, from 95 studies, were identified to include in our review. Two main clinical phenotypes (ulcerative lesions and mucous patches) appeared to be of particular relevance to oral manifestations. A solitary ulcer was mostly manifested as the lesion of primary syphilis (91.7%) preferentially located on the upper lip, tongue, palate, and buccal mucosa. The most affected anatomical site in the patients with single location involved was the tongue (37.5%), followed by the lips (29.5%), palates (19.3%), and buccal mucosa (6.8%). It is concluded that oral syphilis has its predominant clinical phenotypes although it can manifest in diverse manners. Lippincott Williams & Wilkins 2021-12 2021-08-25 /pmc/articles/PMC8594522/ /pubmed/34433795 http://dx.doi.org/10.1097/OLQ.0000000000001538 Text en Copyright © 2021 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Sexually Transmitted Diseases Association. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. |
spellingShingle | Reviews Zhou, Xiao Wu, Min-Zhi Jiang, Ting-Ting Chen, Xiang-Sheng Oral Manifestations of Early Syphilis in Adults: A Systematic Review of Case Reports and Series |
title | Oral Manifestations of Early Syphilis in Adults: A Systematic Review of Case Reports and Series |
title_full | Oral Manifestations of Early Syphilis in Adults: A Systematic Review of Case Reports and Series |
title_fullStr | Oral Manifestations of Early Syphilis in Adults: A Systematic Review of Case Reports and Series |
title_full_unstemmed | Oral Manifestations of Early Syphilis in Adults: A Systematic Review of Case Reports and Series |
title_short | Oral Manifestations of Early Syphilis in Adults: A Systematic Review of Case Reports and Series |
title_sort | oral manifestations of early syphilis in adults: a systematic review of case reports and series |
topic | Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594522/ https://www.ncbi.nlm.nih.gov/pubmed/34433795 http://dx.doi.org/10.1097/OLQ.0000000000001538 |
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