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Targeting the coronavirus nucleocapsid protein through GSK-3 inhibition

The coronaviruses responsible for severe acute respiratory syndrome (SARS-CoV), COVID-19 (SARS-CoV-2), Middle East respiratory syndrome-CoV, and other coronavirus infections express a nucleocapsid protein (N) that is essential for viral replication, transcription, and virion assembly. Phosphorylatio...

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Detalles Bibliográficos
Autores principales: Liu, Xiaolei, Verma, Anurag, Garcia, Gustavo, Ramage, Holly, Lucas, Anastasia, Myers, Rebecca L., Michaelson, Jacob J., Coryell, William, Kumar, Arvind, Charney, Alexander W., Kazanietz, Marcelo G., Rader, Daniel J., Ritchie, Marylyn D., Berrettini, Wade H., Schultz, David C., Cherry, Sara, Damoiseaux, Robert, Arumugaswami, Vaithilingaraja, Klein, Peter S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594528/
https://www.ncbi.nlm.nih.gov/pubmed/34593624
http://dx.doi.org/10.1073/pnas.2113401118