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Heightened Virulence of Yersinia Is Associated with Decreased Function of the YopJ Protein

Despite the maintenance of YopP/J alleles throughout the human-pathogenic Yersinia lineage, the benefit of YopP/J-induced phagocyte death for Yersinia pathogenesis in animals is not obvious. To determine how the sequence divergence of YopP/J has impacted Yersinia virulence, we examined protein polym...

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Detalles Bibliográficos
Autores principales: Mares, Chris A., Lugo, Fernando P., Albataineh, Mohammad, Goins, Beth A., Newton, Irene G., Isberg, Ralph R., Bergman, Molly A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594599/
https://www.ncbi.nlm.nih.gov/pubmed/34543120
http://dx.doi.org/10.1128/IAI.00430-21