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Mucosal Immunization with DTaP Confers Protection against Bordetella pertussis Infection and Cough in Sprague-Dawley Rats

Pertussis is a respiratory disease caused by the Gram-negative pathogen, Bordetella pertussis. The transition from a whole-cell pertussis vaccine (wP and DTP) to an acellular pertussis vaccine (aP, DTaP, and Tdap) correlates with an increase in pertussis cases, despite widespread vaccine implementat...

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Detalles Bibliográficos
Autores principales: Hall, Jesse M., Bitzer, Graham J., DeJong, Megan A., Kang, Jason, Wong, Ting Y., Wolf, M. Allison, Bevere, Justin R., Barbier, Mariette, Damron, F. Heath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594602/
https://www.ncbi.nlm.nih.gov/pubmed/34516235
http://dx.doi.org/10.1128/IAI.00346-21

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