Cargando…

The EpiDiverse Plant Epigenome-Wide Association Studies (EWAS) Pipeline

Bisulfite sequencing is a widely used technique for determining DNA methylation and its relationship with epigenetics, genetics, and environmental parameters. Various techniques were implemented for epigenome-wide association studies (EWAS) to reveal meaningful associations; however, there are only...

Descripción completa

Detalles Bibliográficos
Autores principales: Can, Sultan Nilay, Nunn, Adam, Galanti, Dario, Langenberger, David, Becker, Claude, Volmer, Katharina, Heer, Katrin, Opgenoorth, Lars, Fernandez-Pozo, Noe, Rensing, Stefan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594691/
https://www.ncbi.nlm.nih.gov/pubmed/34968299
http://dx.doi.org/10.3390/epigenomes5020012
Descripción
Sumario:Bisulfite sequencing is a widely used technique for determining DNA methylation and its relationship with epigenetics, genetics, and environmental parameters. Various techniques were implemented for epigenome-wide association studies (EWAS) to reveal meaningful associations; however, there are only very few plant studies available to date. Here, we developed the EpiDiverse EWAS pipeline and tested it using two plant datasets, from P. abies (Norway spruce) and Q. lobata (valley oak). Hence, we present an EWAS implementation tested for non-model plant species and describe its use.