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Remote Spatiotemporal Control of a Magnetic and Electroconductive Hydrogel Network via Magnetic Fields for Soft Electronic Applications

[Image: see text] Multifunctional hydrogels are a class of materials offering new opportunities for interfacing living organisms with machines due to their mechanical compliance, biocompatibility, and capacity to be triggered by external stimuli. Here, we report a dual magnetic- and electric-stimuli...

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Autores principales: Puiggalí-Jou, Anna, Babeli, Ismael, Roa, Joan Josep, Zoppe, Justin O., Garcia-Amorós, Jaume, Ginebra, Maria-Pau, Alemán, Carlos, García-Torres, Jose
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594865/
https://www.ncbi.nlm.nih.gov/pubmed/34469100
http://dx.doi.org/10.1021/acsami.1c12458
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author Puiggalí-Jou, Anna
Babeli, Ismael
Roa, Joan Josep
Zoppe, Justin O.
Garcia-Amorós, Jaume
Ginebra, Maria-Pau
Alemán, Carlos
García-Torres, Jose
author_facet Puiggalí-Jou, Anna
Babeli, Ismael
Roa, Joan Josep
Zoppe, Justin O.
Garcia-Amorós, Jaume
Ginebra, Maria-Pau
Alemán, Carlos
García-Torres, Jose
author_sort Puiggalí-Jou, Anna
collection PubMed
description [Image: see text] Multifunctional hydrogels are a class of materials offering new opportunities for interfacing living organisms with machines due to their mechanical compliance, biocompatibility, and capacity to be triggered by external stimuli. Here, we report a dual magnetic- and electric-stimuli-responsive hydrogel with the capacity to be disassembled and reassembled up to three times through reversible cross-links. This allows its use as an electronic device (e.g., temperature sensor) in the cross-linked state and spatiotemporal control through narrow channels in the disassembled state via the application of magnetic fields, followed by reassembly. The hydrogel consists of an interpenetrated polymer network of alginate (Alg) and poly(3,4-ethylenedioxythiophene) (PEDOT), which imparts mechanical and electrical properties, respectively. In addition, the incorporation of magnetite nanoparticles (Fe(3)O(4) NPs) endows the hydrogel with magnetic properties. After structural, (electro)chemical, and physical characterization, we successfully performed dynamic and continuous transport of the hydrogel through disassembly, transporting the polymer–Fe(3)O(4) NP aggregates toward a target using magnetic fields and its final reassembly to recover the multifunctional hydrogel in the cross-linked state. We also successfully tested the PEDOT/Alg/Fe(3)O(4) NP hydrogel for temperature sensing and magnetic hyperthermia after various disassembly/re-cross-linking cycles. The present methodology can pave the way to a new generation of soft electronic devices with the capacity to be remotely transported.
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spelling pubmed-85948652021-11-19 Remote Spatiotemporal Control of a Magnetic and Electroconductive Hydrogel Network via Magnetic Fields for Soft Electronic Applications Puiggalí-Jou, Anna Babeli, Ismael Roa, Joan Josep Zoppe, Justin O. Garcia-Amorós, Jaume Ginebra, Maria-Pau Alemán, Carlos García-Torres, Jose ACS Appl Mater Interfaces [Image: see text] Multifunctional hydrogels are a class of materials offering new opportunities for interfacing living organisms with machines due to their mechanical compliance, biocompatibility, and capacity to be triggered by external stimuli. Here, we report a dual magnetic- and electric-stimuli-responsive hydrogel with the capacity to be disassembled and reassembled up to three times through reversible cross-links. This allows its use as an electronic device (e.g., temperature sensor) in the cross-linked state and spatiotemporal control through narrow channels in the disassembled state via the application of magnetic fields, followed by reassembly. The hydrogel consists of an interpenetrated polymer network of alginate (Alg) and poly(3,4-ethylenedioxythiophene) (PEDOT), which imparts mechanical and electrical properties, respectively. In addition, the incorporation of magnetite nanoparticles (Fe(3)O(4) NPs) endows the hydrogel with magnetic properties. After structural, (electro)chemical, and physical characterization, we successfully performed dynamic and continuous transport of the hydrogel through disassembly, transporting the polymer–Fe(3)O(4) NP aggregates toward a target using magnetic fields and its final reassembly to recover the multifunctional hydrogel in the cross-linked state. We also successfully tested the PEDOT/Alg/Fe(3)O(4) NP hydrogel for temperature sensing and magnetic hyperthermia after various disassembly/re-cross-linking cycles. The present methodology can pave the way to a new generation of soft electronic devices with the capacity to be remotely transported. American Chemical Society 2021-09-01 2021-09-15 /pmc/articles/PMC8594865/ /pubmed/34469100 http://dx.doi.org/10.1021/acsami.1c12458 Text en © 2021 American Chemical Society https://creativecommons.org/licenses/by/4.0/Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Puiggalí-Jou, Anna
Babeli, Ismael
Roa, Joan Josep
Zoppe, Justin O.
Garcia-Amorós, Jaume
Ginebra, Maria-Pau
Alemán, Carlos
García-Torres, Jose
Remote Spatiotemporal Control of a Magnetic and Electroconductive Hydrogel Network via Magnetic Fields for Soft Electronic Applications
title Remote Spatiotemporal Control of a Magnetic and Electroconductive Hydrogel Network via Magnetic Fields for Soft Electronic Applications
title_full Remote Spatiotemporal Control of a Magnetic and Electroconductive Hydrogel Network via Magnetic Fields for Soft Electronic Applications
title_fullStr Remote Spatiotemporal Control of a Magnetic and Electroconductive Hydrogel Network via Magnetic Fields for Soft Electronic Applications
title_full_unstemmed Remote Spatiotemporal Control of a Magnetic and Electroconductive Hydrogel Network via Magnetic Fields for Soft Electronic Applications
title_short Remote Spatiotemporal Control of a Magnetic and Electroconductive Hydrogel Network via Magnetic Fields for Soft Electronic Applications
title_sort remote spatiotemporal control of a magnetic and electroconductive hydrogel network via magnetic fields for soft electronic applications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594865/
https://www.ncbi.nlm.nih.gov/pubmed/34469100
http://dx.doi.org/10.1021/acsami.1c12458
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