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The chromatin-remodeling enzyme Smarca5 regulates erythrocyte aggregation via Keap1-Nrf2 signaling

Although thrombosis has been extensively studied using various animal models, our understanding of the underlying mechanism remains elusive. Here, using zebrafish model, we demonstrated that smarca5-deficient red blood cells (RBCs) formed blood clots in the caudal vein plexus. We further used the an...

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Detalles Bibliográficos
Autores principales: Ding, Yanyan, Li, Yuzhe, Zhao, Ziqian, Cliff Zhang, Qiangfeng, Liu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594921/
https://www.ncbi.nlm.nih.gov/pubmed/34698638
http://dx.doi.org/10.7554/eLife.72557

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