Cargando…
The mammalian rod synaptic ribbon is essential for Ca(v) channel facilitation and ultrafast synaptic vesicle fusion
Rod photoreceptors (PRs) use ribbon synapses to transmit visual information. To signal ‘no light detected’ they release glutamate continually to activate post-synaptic receptors. When light is detected glutamate release pauses. How a rod’s individual ribbon enables this process was studied here by r...
Autores principales: | Grabner, Chad Paul, Moser, Tobias |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594941/ https://www.ncbi.nlm.nih.gov/pubmed/34617508 http://dx.doi.org/10.7554/eLife.63844 |
Ejemplares similares
-
Eliminating Synaptic Ribbons from Rods and Cones Halves the Releasable Vesicle Pool and Slows Down Replenishment
por: Mesnard, Chris S., et al.
Publicado: (2022) -
Acute destruction of the synaptic ribbon reveals a role for the ribbon in vesicle priming
por: Snellman, Josefin, et al.
Publicado: (2011) -
Axonal Synapses Utilize Multiple Synaptic Ribbons in the Mammalian Retina
por: Kim, Hong-Lim, et al.
Publicado: (2012) -
The synaptic ribbon is critical for sound encoding at high rates and with temporal precision
por: Jean, Philippe, et al.
Publicado: (2018) -
Individual synaptic vesicles mediate stimulated exocytosis from cochlear inner hair cells
por: Grabner, Chad Paul, et al.
Publicado: (2018)