A highly conserved host lipase deacylates oxidized phospholipids and ameliorates acute lung injury in mice

Oxidized phospholipids have diverse biological activities, many of which can be pathological, yet how they are inactivated in vivo is not fully understood. Here, we present evidence that a highly conserved host lipase, acyloxyacyl hydrolase (AOAH), can play a significant role in reducing the pro-inf...

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Detalles Bibliográficos
Autores principales: Zou, Benkun, Goodwin, Michael, Saleem, Danial, Jiang, Wei, Tang, Jianguo, Chu, Yiwei, Munford, Robert S, Lu, Mingfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594946/
https://www.ncbi.nlm.nih.gov/pubmed/34783310
http://dx.doi.org/10.7554/eLife.70938

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594946/
https://www.ncbi.nlm.nih.gov/pubmed/34783310
http://dx.doi.org/10.7554/eLife.70938

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