Modulating neuroinflammation in COVID-19 patients with obsessive-compulsive disorder

Exacerbation of symptoms of obsessive-compulsive disorder (OCD) during COVID-19 or new onset of the OCD symptoms resulting from COVID-19 infection is an understudied area of research. It is possible that increased proinflammatory immune status is associated with the onset of obsessive-compulsive sym...

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Autores principales: Nezgovorova, Vera, Ferretti, Casara Jean, Pallanti, Stefano, Hollander, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Ltd. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594960/
https://www.ncbi.nlm.nih.gov/pubmed/34809994
http://dx.doi.org/10.1016/j.jpsychires.2021.11.025
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author Nezgovorova, Vera
Ferretti, Casara Jean
Pallanti, Stefano
Hollander, Eric
author_facet Nezgovorova, Vera
Ferretti, Casara Jean
Pallanti, Stefano
Hollander, Eric
author_sort Nezgovorova, Vera
collection PubMed
description Exacerbation of symptoms of obsessive-compulsive disorder (OCD) during COVID-19 or new onset of the OCD symptoms resulting from COVID-19 infection is an understudied area of research. It is possible that increased proinflammatory immune status is associated with the onset of obsessive-compulsive symptoms in patients with COVID-19 and that targeted anti-inflammatory treatments for COVID-19 infection can mitigate the new onset of Obsessive-Compulsive (OC) spectrum symptoms. In this review, we cover OCD pathogenesis as related to COVID-19, summarize the impact of cytokines on behavior, and suggest that anti-cytokine treatments can help mitigate post-COVID-19 and new onset of the OC symptoms.
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spelling pubmed-85949602021-11-17 Modulating neuroinflammation in COVID-19 patients with obsessive-compulsive disorder Nezgovorova, Vera Ferretti, Casara Jean Pallanti, Stefano Hollander, Eric J Psychiatr Res Article Exacerbation of symptoms of obsessive-compulsive disorder (OCD) during COVID-19 or new onset of the OCD symptoms resulting from COVID-19 infection is an understudied area of research. It is possible that increased proinflammatory immune status is associated with the onset of obsessive-compulsive symptoms in patients with COVID-19 and that targeted anti-inflammatory treatments for COVID-19 infection can mitigate the new onset of Obsessive-Compulsive (OC) spectrum symptoms. In this review, we cover OCD pathogenesis as related to COVID-19, summarize the impact of cytokines on behavior, and suggest that anti-cytokine treatments can help mitigate post-COVID-19 and new onset of the OC symptoms. Published by Elsevier Ltd. 2022-05 2021-11-17 /pmc/articles/PMC8594960/ /pubmed/34809994 http://dx.doi.org/10.1016/j.jpsychires.2021.11.025 Text en © 2021 Published by Elsevier Ltd. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Nezgovorova, Vera
Ferretti, Casara Jean
Pallanti, Stefano
Hollander, Eric
Modulating neuroinflammation in COVID-19 patients with obsessive-compulsive disorder
title Modulating neuroinflammation in COVID-19 patients with obsessive-compulsive disorder
title_full Modulating neuroinflammation in COVID-19 patients with obsessive-compulsive disorder
title_fullStr Modulating neuroinflammation in COVID-19 patients with obsessive-compulsive disorder
title_full_unstemmed Modulating neuroinflammation in COVID-19 patients with obsessive-compulsive disorder
title_short Modulating neuroinflammation in COVID-19 patients with obsessive-compulsive disorder
title_sort modulating neuroinflammation in covid-19 patients with obsessive-compulsive disorder
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594960/
https://www.ncbi.nlm.nih.gov/pubmed/34809994
http://dx.doi.org/10.1016/j.jpsychires.2021.11.025
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