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Nrf3 Promotes 5-FU Resistance in Colorectal Cancer Cells via the NF-κB/BCL-2 Signaling Pathway In Vitro and In Vivo

Increasing evidence indicates that nuclear factor, erythroid 2-like 3 (Nrf3) is connected with tumorigenesis. However, the relationship between Nrf3 and tumor drug resistance remains elusive. In this study, we investigated the effect and mechanism of action by which Nrf3 regulated the sensitivity of...

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Detalles Bibliográficos
Autores principales: Cai, Bi-Qing, Chen, Wan-Meng, Zhao, Jia, Hou, Wei, Tang, Jian-Cai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595022/
https://www.ncbi.nlm.nih.gov/pubmed/34795760
http://dx.doi.org/10.1155/2021/9355555