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SETD1A Mediated H3K4 Methylation and Its Role in Neurodevelopmental and Neuropsychiatric Disorders

Posttranslational modification of histones and related gene regulation are shown to be affected in an increasing number of neurological disorders. SETD1A is a chromatin remodeler that influences gene expression through the modulation of mono- di- and trimethylation marks on Histone-H3-Lysine-4 (H3K4...

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Detalles Bibliográficos
Autores principales: Wang, Shan, Bleeck, Anna, Nadif Kasri, Nael, Kleefstra, Tjitske, van Rhijn, Jon-Ruben, Schubert, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595121/
https://www.ncbi.nlm.nih.gov/pubmed/34803610
http://dx.doi.org/10.3389/fnmol.2021.772000