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SETD1A Mediated H3K4 Methylation and Its Role in Neurodevelopmental and Neuropsychiatric Disorders
Posttranslational modification of histones and related gene regulation are shown to be affected in an increasing number of neurological disorders. SETD1A is a chromatin remodeler that influences gene expression through the modulation of mono- di- and trimethylation marks on Histone-H3-Lysine-4 (H3K4...
Autores principales: | Wang, Shan, Bleeck, Anna, Nadif Kasri, Nael, Kleefstra, Tjitske, van Rhijn, Jon-Ruben, Schubert, Dirk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595121/ https://www.ncbi.nlm.nih.gov/pubmed/34803610 http://dx.doi.org/10.3389/fnmol.2021.772000 |
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